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VOLUME 3 , ISSUE 1 ( January-April, 2010 ) > List of Articles

CASE REPORT

Isolated Orbital Aspergillosis in an Immunocompetent Patient

Devinder Pal Singh, Anish K Gupta, Kuldip Singh

Keywords : Orbital,aspergillosis,voriconazole,immunocompetent

Citation Information : Singh DP, Gupta AK, Singh K. Isolated Orbital Aspergillosis in an Immunocompetent Patient. Clin Rhinol An Int J 2010; 3 (1):53-55.

DOI: 10.5005/jp-journals-10013-1029

Published Online: 01-04-2010

Copyright Statement:  Copyright © 2010; The Author(s).


Abstract

A 30-year-old immunocompetent male presented with progressive painless proptosis with double vision and no visual loss. The patient had a mass lesion in the lateral part of the orbit infiltrating the lateral rectus on computed tomography. Lateral orbitotomy was done and the mass was biopsied revealing it to be aspergillosis. The patient was put on intravenous amphotericin B but did not tolerate it and was therefore started on voriconazole. There was a complete resolution of the symptoms with voriconazole.


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  1. Sino-orbital and cerebral aspergillosis: Cure with medical therapy. Mykosen 1987;30:379-85.
  2. Aspergillosis of the orbit. Arch Ophthalmol 1969;82:302-13.
  3. Sino-orbital aspergillosis treated with combination antifungal therapy. Successful therapy after failure with amphotericin B and surgery. JAMA 1980;244:814-15.
  4. The spectrum of orbital aspergillosis: A clinicopathological review. Surv Ophthalmol 1996;41:142-54.
  5. Sinonasal aspergillosis in immunocompetent Indian children: An eight-year experience. Mycoses 2003;46(11-12):455-61.
  6. Postgraduate institute management protocol for the management of aspergillus flavus sinusitis: Is it effective? Int J Inf Dis 2009;13(2):134-39.
  7. Invasive rhinosinoorbital aspergillosis with precipitous visual loss. Can J Ophthalmol 1995;30:124-30.
  8. Orbital aspergillosis. Report of a case diagnosed by fine needle aspiration biopsy. Acta Cytol 1983;27:166-69.
  9. Proptosis as the initial presentation of fungal sinusitis in immunocompetent patients. Ophthalmology 1995;102:713-17.
  10. Cerebral and orbital aspergillus infection due to invasive aspergillosis of ethmoid sinus. J Clin Pathol 1986;39:774-78.
  11. Aspergillus aneurysm of the middle cerebral artery causing a fatal subarachnoid hemorrhage. Intern Med 1995;34:550-53.
  12. In vitro susceptibility and synergy studies of aspergillus species to conventional and new agents. Diagn Microbiol Infect Dis 1992;15:21-34.
  13. Aspergillus species. In: Mandell GL, Bennett JE, Dolin R (Eds). Principles and Practice of Infectious Diseases (5th ed). Philadelphia: Churchill Livingstone 2000;2:2674-85.
  14. Itraconazole in the treatment of orbital aspergillosis. Ophthalmology 1996;103:1467-70.
  15. Successful treatment of an invasive aspergillosis of the skull base and paranasal sinuses with liposomal amphotericin B and itraconazole. Ann Otol Rhinol Laryngol 1999;108:205-07.
  16. Host defense mechanisms in aspergillus fumigatus infections. Contrib Microbiol 1999;2:57-68.
  17. Treatment of invasive Aspergillus sinusitis with liposomal-amphotericin B. Laryngoscope 1987;97:937-41.
  18. Practice guidelines for disease caused by aspergillus. Clin Infect Dis 2000;30:696-709.
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