A Rare Case of Tuberous Xanthoma of Nose: A Case Report
KG Somashekara, Apurva A Jarandikar, Lakshmi Shantharam, Hemalatha Mahantappa
Keywords :
Benign fibrous histiocytoma, Case report, Deformed nose, Nasal septum, Nose, Open rhinoplasty, Paranasal sinus
Citation Information :
Somashekara K, Jarandikar AA, Shantharam L, Mahantappa H. A Rare Case of Tuberous Xanthoma of Nose: A Case Report. Clin Rhinol An Int J 2023; 14 (1--3):20-22.
Xanthomas are localized lipid deposits in organs that may manifest as papules, plaques, or nodules on skin. There are many variants of xanthomas, and tuberous xanthoma is one of the xanthomas. They are very rare in head and neck region and xanthoma of the nose has been reported only once before. Xanthomas elsewhere are excised mainly for diagnostic purpose, whereas our patient wanted excision for better cosmetic appearance of the nose. We are presenting this case for its rarity and for concerns in management with review of literature. Facial xanthoma management requires excision for diagnosis and cosmesis. However, management of underlying lipid disorder is also very essential.
Vargas-Flores E, Lourdes Estrada-Alpizar E, Arenas-Osuna J. Tuberous xanthomatosis as a presentation of familial hypercholesterolemia. JSM Clin Case Rep 2016;4:1114. DOI: https://doi.org/10.47739/2373-9819/1114.
Pathania V, Yadav A. A case of familial hypercholesterolaemia Type IIa presenting with tuberous xanthomas. Med J Armed Forces India 2015;71(Suppl 1):S254–S256. DOI: 10.1016/j.mjafi.2014.07.004.
Babu R, Venkataram A, Santhosh S, et al. Giant Tuberous Xanthomas in a case of Type IIA Hypercholesterolemia. J Cutan Aesthet Surg 2012;5(3):204–206. DOI: 10.4103/0974-2077.101384.
Zak A, Zeman M, Slaby A, et al. Xanthomas: Clinical and Pathophysiological relations. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014;158(2):181–188. DOI: 10.5507/bp.2014.016.
Pitman M, Elhosseiny A, Moscatello AL. Xanthoma of the maxillary sinus. Otolaryngol Head Neck Surg 2002;126(4):426–427. DOI: 10.1067/mhn.2002.123832.
Muthuswamy KA, Azmi K, Narayan P. Bilateral temporal bone xanthoma: Case report. J Neurosurg 2008;108(2):361–364. DOI: 10.3171/JNS/2008/108/2/0361.
Morel D, Kelsch RD, Nolan PJ. Primary xanthoma of the mandible: Report of a rare case. Head Neck Pathol 2016;10(2):245–251. DOI: 10.1007/s12105-015-0643-z.
Nam MH, Grande JP, Li CY, et al. Familial hypercholesterolemia with unusual foamy histiocytes. Report of a case with myelophthisic anemia and xanthoma of the maxillary sinus. Am J Clin Pathol 1988;89(4):556–561. DOI: 10.1093/ajcp/89.4.556.
Mercado G JA, Torre CA, Hernandez G, et al. Xanthoma of the Sphenoid Sinus: A Rare Presentation. Otolaryngol Head and Neck Surg 2013;149:266. DOI:10.1177/0194599813496044a374.
Fujiwara S, Oka M, Kunisada M, et al. Severe Xanthomatosis with prominent tuberous xanthomas on the cheeks and the nasal dorsum in a patient with type IIa hyperlipoproteinemia. Eur J Dermatol 2013;23(4):517–518. DOI: 10.1684/ejd.2013.2063.