Citation Information :
Subramanian R, Narayan V, Shankar G. Comparative Study of Nasal MCC in Post-FESS and Healthy Individuals Using Saccharin Test. Clin Rhinol An Int J 2024; 15 (2):54-57.
Aims and objective: To demonstrate the ciliary function in postendoscopic sinus surgery patients clinically and compare with that of normal individuals using Saccharin test.
Materials and methods: It is a comparative study between the mucociliary clearance (MCC) of healthy individuals and post-endoscopic sinus surgery individuals. The study group people who fit in the inclusion and exclusion criteria are divided into two groups A and B. Group A candidates are healthy adult individuals while group B candidates are post-surgical patients. With the help of 0-degree nasal endoscope a crystal of Saccharin is placed on the floor of the left nasal cavity at the level of the anterior end of the inferior turbinate. The time taken for the perception of the taste of the Saccharin is noted and results are analyzed.
Results: Endoscopic sinus surgery has not reduced the mucociliary clearance mechanism in our study group patients as the time taken by the group B candidates for perception of the taste of Saccharin matches with that of the group A candidates.
Andersen I, Camner P, Jensen PL, et al. A comparison of nasal and tracheobronchial clearance. Arch Environ Health 1974;29(5):290–293. PMID: 4472935.
Hafner B, Davris S, Reichelmann H, et al. Endonasal sinus surgery improves mucociliary transport in severe chronic sinusitis. Am J Rhinol 1997;11(4):271–274. DOI: 10.2500/105065897781446612.
Elwany S, Hisham M, Gamaee R. The effect of endoscopic sinus surgery on mucociliary clearance in patients with chronic sinusitis. Eur Arch Otorhinolaryngol 1998;225:511– 514. DOI: 10.1007/s004050050109.
Gelardi M, Guglielmi AV, De Candia N, et al. Effect of sodium hyaluronate on mucociliary clearance after functional endoscopic sinus surgery. Eur Ann Allergy Clin Immunol 2013;45(3):103–108. PMID: 23862400.
Pradhan B, Thapa N. Functional endoscopic sinus surgery (FESS). JNMA J Nepal Med Assoc. 2006;45(164):337–341. PMID: 17676068.
Shusterman D. A simplified technique for evaluating nasal muco-ciliary clearance via saccharin transit time. Int Forum Allergy Rhinol 2020;10(4):572–574. DOI: 10.1002/alr.22528.
Aroor R, Sunu Ali Z, Gangadhara Somayaji KS. Do Nasal Surgeries Affect Muco-ciliary Clearance? Indian J Oto laryngol Head Neck Surg 2017;69(1):24–28. DOI: 10.1007/s12070-016-1016-y.
Pandya VK, Tiwari RS. Nasal muco-ciliary clearance in health and disease. Indian J Otolaryngol Head Neck Surg. 2006;58(4):332–334. DOI: 10.1007/BF03049581.
Proctor DF, Andersen I. Nasal muco-ciliary function in normal man. Rhinology 1976;14:11–17. PMID: 1273411.
Passali D, Bellussi L, Bianchini Ciampoli M, et al. Experiences in the determination of nasal mucociliary transport time. Acta Otolaryngol 1984;97:319–323. DOI: 10.3109/00016488409130995.
Moriyama H, Yanagi K, Ohtori N, et al. Healing process of sinus mucosa after endoscopic sinus surgery. Am J Rhinol 1996;10:61–66. DOI: 10.2500/105065896781795067.
Moriyama H, Yanagi K, Ohtori N, et al. Evaluation of endoscopic sinus surgery for chronic sinusitis: Post-operative erythromycin therapy. Rhinology 1995;33(3):166–170. PMID: 8560171.
Sakakura Y. Nasal mucociliary clearance under various conditions. Acta Otolaryngol (Stochh) 1983;96:167–173. DOI: 10.3109/00016488309132888.
Burgersdijk FJA, De Groot JCMJ, Graamans K, et al. Testing ciliary activity in patients with chronic and recurrent infections of the upper airways: Experiences in 68 cases. Laryngoscope 1986;96:1029–1033. PMID: 3528726.
Sakakura Y, Ukai K, Yamagiwa M, et al. Nasal mucociliary function in man. J Otolaryngol Jpn 1980;83:1592–1598. PMID: 6973014.
King E. A clinical study of the functioning of the maxillary sinus mucosa. Ann Oto/Laryngol 1935;44:480–482. DOI: 10.1177/0003489435044002.