Introduction: Unilateral sinonasal masses are frequently encountered and a benign appearance may conceal their true malignant nature. This study aimed to investigate the clinical presentations of unilateral sinonasal masses, analyze their radiological results, and establish a correlation with histological findings. Materials and methods: The study was conducted on 81 patients who presented with a unilateral sinonasal mass at our ENT department, Command Hospital Air Force Bengaluru, between 2014 and 2016. The patients had routine hematological and biochemical tests, diagnostic nasal endoscopy, and NCCT/MRI of the paranasal sinuses. A preoperative biopsy was performed if deemed necessary. Following the initial evaluation, the patient underwent either endoscopic or open operation. The histological examination and immunohistochemistry results were then analyzed and evaluated. Results and observations: The study revealed the presence of 44 cases of inflammatory polyps, 3 cases of adenoid cystic carcinoma, 19 cases of inverted papilloma, 5 cases of fungal sinusitis, and 3 cases of squamous carcinoma. Additionally, there was one case each of solitary fibrous tumor, angiofibroma, odontogenic keratinizing tumor, Non-Hodgkins lymphoma, adenocarcinoma, and acinic cell tumor. A detailed review of the clinical, radiographic, and histological data was conducted for all 81 cases of unilateral sinonasal mass. Conclusion: Thorough assessment of sinonasal masses using radiographic, histological, and immunohistochemical methods improves in precise diagnosis and appropriate treatment. Histopathology usually offers a definitive diagnosis; however, in certain cases, immunohistochemistry serves as the ultimate diagnostic method for correct identification.