Clinical Rhinology

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VOLUME 12 , ISSUE 1 ( January-April, 2019 ) > List of Articles


Sinonasal Undifferentiated Carcinoma: A Rare Entity

Mohamed Dhaha, Sawssen Dhambri, Souheil Jbali, Makram Tibini, Slim Touati, Skander Kedous, Said Gritli

Citation Information : Dhaha M, Dhambri S, Jbali S, Tibini M, Touati S, Kedous S, Gritli S. Sinonasal Undifferentiated Carcinoma: A Rare Entity. Clin Rhinol An Int J 2019; 12 (1):21-23.

DOI: 10.5005/jp-journals-10013-1354

License: CC BY-NC 4.0

Published Online: 10-02-2021

Copyright Statement:  Copyright © 2019; The Author(s).


Malignant tumors of sinonasal tract are rare, representing only 3% of head and neck cancers. Sinonasal undifferentiated carcinoma (SNUC) is a rare entity recently described by Frierson et al. in 1986. Many clinical and pathological aspects of this disease remain misunderstood. We report the case of 52-year-old male suffering from a rapidly fatal SNUC of the right nasal cavity. We tried to focus on the clinical and histological presentations of the disease, and we discussed the different possible treatment modalities, which are still guided by small retrospective studies. SNUC is a rare entity. Its management is challenging due to its local aggressive behavior and high propensity to metastasis. There is no evidence that aggressive therapy offers better survival. A better comprehension of the disease is necessary.

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