An International Journal Clinical Rhinology

Register      Login

VOLUME 10 , ISSUE 3 ( 2017 ) > List of Articles

ORIGINAL ARTICLE

Visual Outcome in Patients with Acute Invasive Fungal Rhinosinusitis

PK Rathore, Vikas Malhotra, Anuragini Gupta

Keywords : Acute invasive fungal rhinosinusitis, Fungal rhinosinusitis, Invasive aspergillosis, Rhino-orbital aspergillosis

Citation Information : Rathore P, Malhotra V, Gupta A. Visual Outcome in Patients with Acute Invasive Fungal Rhinosinusitis. Clin Rhinol An Int J 2017; 10 (3):120-123.

DOI: 10.5005/jp-journals-10013-1321

License: CC BY-ND 3.0

Published Online: 01-12-2017

Copyright Statement:  Copyright © 2017; The Author(s).


Abstract

Acute invasive fungal rhinosinusitis (AIFRS) is an aggressive disease with fatal complications. The mortality rate of AIFRS ranges between 49 and 62%. The incidence of visual loss in AIFRS has been reported to be between 26 and 29%. A total of 5/16 patients in our study showed improvement in vision after treatment in 1 year follow-up while 11 patients showed no improvement in visual acuity. The AIFRS with visual loss is managed using systemic amphotericin B with a combination of surgical debridement.


PDF Share
  1. Chen C-Y, Sheng W-H, Cheng A, Chen YC, Tsay W, Tang JL, Huang SY, Chang SC, Tien HF. Invasive fungal sinusitis in patients with hematological malignancy: 15 years experience in a single university hospital in Taiwan. BMC Infect Dis 2011 Sep;11:250.
  2. Drakos PE, Nagler A, Or R, Naparstek E, Kapelushnik J, Engelhard D, Rahav G, Ne'emean D, Slavin S. Invasive fungal sinusitis in patients undergoing bone marrow transplantation. Bone Marrow Transplant 1993 Sep;12(3):203-208.
  3. Parikh SL, Venkatraman G, DelGaudio JM. Invasive fungal sinusitis: a 15-year review from a single institution. Am J Rhinol 2004 Mar-Apr;18(2):75-81.
  4. Monroe MM, McLean M, Sautter N, Wax MK, Andersen PE, Smith TL, Gross ND. Invasive fungal rhinosinusitis: a 15-year experience with 29 patients. Laryngoscope 2013 Jul;123(7):1583-1587.
  5. DelGaudio JM, Clemson LA. An early detection protocol for invasive fungal sinusitis in neutropenic patients successfully reduces extent of disease at presentation and long term morbidity. Laryngoscope 2009 Jan;119(1):180-183.
  6. Valera FCP, do Lago T, Tamashiro E, Yassuda CC, Silveira F, Anselmo-Lima WT. Prognosis of acute invasive fungal rhinosinusitis related to underlying disease. Int J Infect Dis 2011 Dec;15(12):e841-e844.
  7. Cho H-J, Jang M-S, Hong SD, Chung S-K, Kim HY, DhongHJ. Prognostic factors for survival in patients with acute invasive fungal rhinosinusitis. Am J Rhinol Allergy 2015 Jan-Feb;29(1):48-53.
  8. deShazo RD, O'Brien M, Chapin K, Soto-Aguilar M, Gardner L, Swain R. A new classification and diagnostic criteria for invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg 1997 Nov;123(11):1181-1188.
  9. Chakrabarti A, Denning DW, Ferguson BJ, Ponikau J, Buzina W, Kita H, Marple B, Panda N, Vlaminck S, Kauffmann-Lacroix C, et al. Fungal rhinosinusitis: a categorization and definitional schema addressing current controversies. Laryngoscope 2009 Sep;119(9):1809-1818.
  10. Siddiqui AA, Shah AA, Bashir SH. Craniocerebral aspergillosis of sinonasal origin in immunocompetent patients: clinical spectrum and outcome in 25 cases. Neurosurgery 2004 Sep;55(3):602-611; discussion 611-3.
  11. McGill TJ, Simpson G, Healy GB. Fulminant aspergillosis of the nose and paranasal sinuses: a new clinical entity. Laryngoscope 1980 May;90(5 Pt 1):748-754.
  12. Ferguson BJ. Definitions of fungal rhinosinusitis. Otolaryngol Clin North Am 2000 Apr;33(2):227-235.
  13. Lin SJ, Schranz J, Teutsch SM. Aspergillosis case-fatality rate: systematic review of the literature. Clin Infect Dis 2001 Feb;32(3):358-366. Epub 2001 Jan 26.
  14. Payne SJ, Mitzner R, Kunchala S, Roland L, McGinn JD. Acute invasive fungal rhinosinusitis: a 15-year experience with 41 patients. Otolaryngol Head Neck Surg 2016 Apr;154(4): 759-764. Epub 2016 Feb 16.
  15. Bhansali A, Bhadada S, Sharma A, Suresh V, Gupta A, Singh P, Chakarbarti A, Dash RJ. Presentation and outcome of rhinoorbital- cerebral mucormycosis in patients with diabetes. Post Graduate Med J 2004 Nov;80(949):670-674.
  16. Boelaert JR. Mucormycosis (zygomycosis): is there news for the clinician. J Infect 1994 May;28(Suppl 1):1-6.
  17. Sugar AM. Mucormycosis. Clin Infect 1992;14:126-129.
  18. Avet PP, Kline LB, Sillers MJ. Endoscopic sinus surgery in the management of mucormycosis. J Neuroophthalmol 1999 Mar;19(1):56-61.
  19. Bhattacharyya N. Bacterial infection in chronic rhinosinusitis: a controlled paired analysis. Am J Rhinol 2005 Nov- Dec;19(6):544-548.
  20. Boase S, Foreman A, Cleland E, Tan L, Melton-Kroft R, Pant H, Hu FZ, Ehrlich GD, Wormald PJ. The microbiome of chronic rhinosinusitis: culture, molecular diagnostics and biofilm detection. BMC Infect Dis 2013 May;13:210.
  21. Mantovani K, Bisanha AA, Demarco RC, Tamashiro E, Martinez R, Anselmo-Lima WT. Maxillary sinuses microbiology from patients with chronic rhinosinusitis. Braz J Otorhinolaryngol 2010 Sep-Oct;76(5):548-551.
  22. Brook I, Gober AE. Recovery of potential pathogens in the nasopharynx of healthy and otitis media-prone children and their smoking and nonsmoking parents. Ann Otol Rhinol Laryngol 2008 Oct;117(10):727-730.
  23. Wu J, Peters BA, Dominianni C, Zhang Y, Pei Z, Yang L, Ma Y, Purdue MP, Jacobs EJ, Gapstur SM, et al. Cigarette smoking and the oral microbiome in a large study of American adults. ISME J 2016 Mar;10(10):2435-2446.
  24. Ertel A, Eng R, Smith SM. The differential effect of cigarette smoke on the growth of bacteria found in humans. Chest 1991 Sep;100(3):628-630.
  25. Reh DD, Higgins TS, Smith TL. Impact of tobacco smoke on chronic rhinosinusitis: a review of the literature. Int Forum Allergy Rhinol 2012 Sep-Oct;2(5):362-369.
  26. Lee KI, Kim DW, Kim EH, Kim JH, Samivel R, Kwon JE, Ahn JC, Chung YJ, Mo JH. Cigarette smoke promotes eosinophilic inflammation, airway remodeling, and nasal polyps in a murine polyp model. Am J Rhinol Allergy 2014 May-Jun;28(3):208-214.
  27. Kumar PS, Matthews CR, Joshi V, de Jager M, Aspiras M. Tobacco smoking affects bacterial acquisition and colonization in oral biofilms. Infect Immun 2011 Nov;79(11): 4730-4738.
  28. Namiot Z, Namiot DB, Kemona A, Gołebiewska M, Bucki R. The effect of cigarette smoking and alcohol consumption on efficacy of Helicobacter pylori eradication. Pol Arch Med Wewn 2000 Sep;104(3):569-574.
  29. Linder JA, Sim I. Antibiotic treatment of acute bronchitis in smokers: a systematic review. J Gen Intern Med 2002 Mar;17(3):230-234.
  30. Lee WK, Ramanathan M Jr, Spannhake EW, Lane AP. The cigarette smoke component acrolein inhibits expression of the innate immune components IL-8 and human betadefensin 2 by sinonasal epithelial cells. Am J Rhinol 2007 Nov-Dec;21(6):658-663.
  31. Kamath PM, Shenoy VS, Mittal N, Sharma NK. Microbiological analysis of paranasal sinuses in chronic sinusitis—a south Indian coastal study. Egypt J Ear Nose Throat All Sci 2013 Nov;14(3):185-189.
  32. Bezerra TF, Pádna FG, Ogawa AI, Gebrim EM, Saldiva PH, Voegels RL. Biofilms in chronic rhinosinusitis with nasal polyps: pilot study. Braz J Otorhinolaryngol 2009 Nov- Dec;75(6):788-793.
  33. Hashemi M, Sadeghi MMM, Omrani MR, Torabi MA. Microbiology and antimicrobial resistance in chronic resistant rhino sinusitis with or without polyp after functional endoscopic sinus surgery. J Res Med Sci 2005;10(3):167-171.
  34. Farahani F, Youse Mashouf R, Hashemian F, Esmaeili R. Antimicrobial resistance patterns of aerobic organisms in patients with chronic rhinosinusitis in Hamadan, Iran. Avicenna J Clin Microb Infec 2014 Aug;1(2):e18961..
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.