Clinical Rhinology

Register      Login

VOLUME 10 , ISSUE 2 ( May-August, 2017 ) > List of Articles


Radiofrequency Turbinoplasty in Imidazoline-induced Rhinitis Medicamentosa

SV Manjunatha Rao

Keywords : Imidazoline,Radiofrequency,Rhinitis medicamentosa

Citation Information : Rao SM. Radiofrequency Turbinoplasty in Imidazoline-induced Rhinitis Medicamentosa. Clin Rhinol An Int J 2017; 10 (2):53-57.

DOI: 10.5005/jp-journals-10013-1307

License: CC BY 3.0

Published Online: 01-12-2009

Copyright Statement:  Copyright © 2017; The Author(s).



To evaluate the efficacy and results of radiofrequency turbinoplasty in patients with rhinitis medicamentosa due to imidazolines like oxymetazoline and xylometazoline.

Study design

This is a prospective, single-blinded, randomized controlled study.

Materials and methods

Study was conducted on 20 patients in a tertiary level center from January 2010 to February 2016. Patients with symptoms and signs of nasal obstruction due to rhinitis medicamentosa were selected. Patients were aged from 16 to 43 years (mean age is 24 years). Twelve were males and eight were females. The duration of use of nasal decongestant drops varied from 3 months to 5 years. The turbinoplasty was performed using the radiofrequency method. Nasal obstruction symptom evaluation (NOSE) questionnaires are used for subjective assessment and nasal endoscopy view score (NES) was used for objective assessment pre- and postoperatively. Follow-up was done at the end of 15 days and 3 months after surgery. The results were statistically analyzed by paired t-test.


The mean NOSE score before procedure was 92. At the 15th postoperative day, mean NOSE score reduced to 1.3 and it further reduced at the 3rd month to 0.5 (p < 0.001), with 99.5% reduction in subjective symptoms. The mean NES before procedure was 3.95. On the 15th day, it was 0.35 and at the end of 3rd month, it was 0 with 91.1% reduction in objective evaluation (p < 0.001). Results were same on left and right side of nose. No major postoperative complication was observed in patients.


Radiofrequency turbinoplasty technique can be recommended as an effective method in imidazoline-induced rhinitis medicamentosa. It is simple, comfortable, fast relief giving, no repeated steroids, and cost-effective, single-session treatment. Good compliance and cooperation from patients can be obtained with no major complications of the treatment. It allows patients to be managed in the office environment.

How to cite this article

Rao SVM. Radiofrequency Turbinoplasty in Imidazoline-induced Rhinitis Medicamentosa. Clin Rhinol An Int J 2017;10(2):53-57.

  1. Rhinitis medicamentosa. Can Med Assoc J 1980 Apr;122(8):881-883.
  2. Rhinitis medicamentosa. J Investig Allergol Clin Immunol 2006;16(3):148-155.
  3. Rhinitis medicamentosa: aspects of pathophysiology and treatment. Allergy 1997 Feb;52(40 Suppl):28-34.
  4. Rhinitis medicamentosa as a cause of increased intraoperative bleeding. Laryngoscope 2010 Oct;120(10):2106-2107.
  5. Mechanisms of vasomotor rhinitis. Allergy 2004 Jan; 59(76):4-10.
  6. Rhinitis during pregnancy and rhinitis medicamentosa. Otolaryngol Head Neck Surg 1992 Dec;107(6 Pt 2): 845-848.
  7. Rhinitis medicamentosa. Clin Exp Allergy 1995 May;25(5):391-394.
  8. Decongestion effect and rebound swelling of the nasal mucosa during 4- week use of oximetazoline. ORL J Otorhinolaryngol Relat Spec 1994 May-Jun;56(3):157-160.
  9. Effect on the nasal mucosa of long-term treatment with oxymetazoline, benzalkonium chloride and placebo nasal sprays. Laryngoscope 1996 May;106(5 Pt 1):605-609.
  10. A study of the effect of nasal steroid sprays in perennial allergic rhinitis patients with rhinitis medicamentosa. Otolaryngol Head Neck Surg 2001 Sep;125(3):3253-3260.
  11. Radiofrequency treatment for inferior turbinate hypertrophy. Kulak Burun Bogaz Ihtis Derg 2011 Jan-Feb;21(1):56-60.
  12. Efficacy of radiofrequency turbinoplasty for treatment of inferior turbinate hypertrophy. Iran J Otorhinolaryngol 2011 Summer;23(3):87-92.
  13. Long-term effect of radiofrequency turbinoplasty in nasal obstruction. Biotechnol Biotechnol Equip 2014 Mar;28(2):285-294.
  14. Rhinitis medicamentosa. Laryngoscope 1981 Oct;91(10):1614-1621.
  15. Long-term results of inferior turbinate hypertrophy with radiofrequency treatment: a new standard of care. Laryngoscope 2006 Apr;116(4):554-557.
  16. Long-term clinical results of radiofrequency tissue volume reduction for inferior turbinate hypertrophy. J Laryngol Otol 2011 Nov;125(11):1148-1151.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.